The ancient city of Puteoli, today Pozzuoli, was an important port of the bay of Naples. But it is also reported as place of production of blue pigments, in the famous book of Vitruvius “The ten books of Architecture” written in Augustus age. Many samples of this pigment are found in Pompeii’s excavations. This blue pigment is first made in ancient Egypt about 2000 BC as a product of the Bronze Age. It is the blue colorant of many potteries, statues and frescos seen in all museums. It is passed early in Europe and we see it in Knossos, Tiryns and Thira. But it is also the main blue pigment of all classic ages and of the early Middle Age. It is suddenly disappeared after 8th century.